PBlue adventures
Top Glove : The E484 mutation
Abstract
The E484, mutation found in emerging SARS-Cov2 viral lineages in Soouth Africa and Brazil reduces neutralization by antibodies from covid19 patients by >10 fold. While the E484 mutation causes significant reduction of antibody binding, it is not the only mutation, other mutations like G485R and S494P also caused lesser but still appreciable (~3 to 5-fold) decreases in neutralization titer
https://www.biorxiv.org/content/10.1101/2020.12.31.425021v1.full.pdf
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Top Glove : Discovery of an infectivity enhancing site on the SARS-Cov2 spike protein.
Created by pBlue | Jan 01, 2021
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