US has 3 greatest setbacks of its own making:

Unilateralism:

US refuses to involve other nations in its foreign affairs. If a government wages war on a neighbouring country without the advice of any outside groups, allies, or nearby countries, it's adopting a policy of unilateralism.

Belligerence:

A belligerent is an individual, group, country, or other entity that acts in a hostile manner, such as engaging in war. US spent 95% of its entire history at war. US has only enjoyed 16 years of peace in its 242-year history.

According to former US President, Jimmy Carter, China loves peace and USA is the MOST warmongering country in the history of humankind.

How do you describe a country which spent 95% of its entire history at war? They have no hesitation to go to war with anyone who do not follow what they want you to do for them and their ideology.

Superior Complex:

US has a superiority complex. US believes its abilities or accomplishments are somehow dramatically better than other people's. People with a superiority complex may be condescending, smug, or mean to other people who don't agree with them.

A very appropriate illustration of what I said above is China-US high-level dialogue held in Alaska last March.

Secretary of State Antony Blinken and National Security Advisor Jake Sullivan commenced the proceedings and made some sharp criticisms of China’s violation of human rights in Xinjiang.

How can it be? The Xinjiang region produces more than 20% of the world's cotton.

In response, Yang Jiechi, a member of the Political Bureau of the Communist Party of China (CPC) Central Committee and director of the Office of the Central Leading Group for Foreign Affairs, gave a bravura performance. Far from pulling his punches or couching his words in diplomatic language, he let his American counterparts have it with both barrels, challenging not just the US position but its very legitimacy. And all this before the world's media. 

“On human rights, we do hope the US will do better on human rights. The challenges facing the US in human rights are deep-seated. They did not just emerge over the past four years, such as Black Lives Matter." "On cyber-attacks, let me say that whether it's the ability to launch cyber-attacks or the technologies that could be deployed, the US is the champion." "The US does not represent international opinion and neither does the Western world."

While delivering these shots, Yang spoke with passion but never raised his voice. There were no cheap jibes. He occupied the high ground in the argument and left the Americans bewildered and belittled.  

This is not normally the Chinese manner on such occasions. It is a sign that something has changed. There is a new sense of confidence on the part of the Chinese. That they are - or can - win the argument. That they are at least the equals of America. That they speak from a position of strength and America from a position of weakness. That history is on their side. It feels like the diplomatic equivalent of moving from "keeping a low profile" to "striving for achievement," or from being a relative spectator in the global system to becoming a major architect. The Americans have hitherto always thought of themselves as running the show; the shock visible in the body language of Blinken and Sullivan was the realization, conscious or unconscious, that this was no longer the case. The same was apparent in the Western media. The BBC, for example, invariably critical of China, reported it with an unfamiliar neutrality, as if stunned by the role reversal.

US President Joe Biden is desperately anxious to appear as hostile to China as Trump was before him. The underlying forces at work here are very deep. America is in the process of coming to the painful realization that China is now its equal. But it cannot bring itself to accept or acquiesce in what is already an historical reality.