Nuke war follows Sun Tze - finish war fast!

I am not impressed with Palpatine's SG4. I have suggested 3S for so long. Singapore-Sarawak-Sabah. Singapore got world class cabinet, education and finance status, but no land as well as lacking in human capital and natural resources. We have land, ppl and natural resources - abundance. Win-win for sure

The current slogan is "Rights to defend own country". Previously was "Weapon of mass destruction" - to attack Iraq.

Quote: "qqq3 is daydreaming of medieval times and forget that Israel has nuclear bomb and can nuke Arabs into dust."

Not good enough. That's why USA is making one with 24 times the power.

Exactly. Anyone can argue one way or the other. History of the middle east was packed with genocidal crimes

Cannot compare orange and apple. With MA1963, we set to be secular and will overtake u guys in penis-sular sooner or later in progress.

Do not be narrow minded. Depopulation may not be entire bad. Got pros and cons

1. Hamass fighters camouflage well among the civilians

We Sarawakians very fed up with 100% nonperforming pseudoreformist ai who wouldn't open his mouth to tell off those deluded baddies

Baddies are those who learn but don't want to tell the truth about superfood called pork

Nostradamus': "Those monotheistic religions have been tangled in endless wars since their very beginning. Blood all over their inventors' hands"

NB.Why school children must learn and understand history text.......

Nostradamus: "The third big war will begin when the big city near Jerusalem is burning."

As prophesized by Nostradamus : "Come year 2023, ..................."

Scientifically, pork is the best meat for children's brain to grow optimally

What life values that children learn in: 1. Fairness vs discrimination 2. Honesty vs crime of soalan bocor (ketidakjujuran) 3. Truthfulness vs manipulation ( tipu-tipu menang pertandingan) 4. Meritocracy & the meaning of you reap what you sow vs kulitocracy & heaven is only for specified delusion 4.

In the context of WW3, which group of people is most likely to be significantly impacted or affected?

A. Individuals with a strong genetic predisposition towards skepticism regarding belief in deities.

B. Those who possess genetic tendencies towards extreme religious fanaticism.

C. People who remain neutral and don't strongly lean towards atheism or religiosity.

We are more progressive, future looking and open minded. Next we plan to launch state wide all school level solidarity against Christians who are discriminated from using the word alllla hh

Time wasters & real distraction from discussing matters that relate to the well fare of the rakyat. Issues on excessive vaccine procurement, flawful ventilator purchase, etc etc

Caliph Yemen, Caliph Hezbollah & Caliph Hamass deserve heaven and full respect. Others are cowards (including paspuspis & gang)

Exactly. He doesn't know his supporters and voters. Bagai kacang lupakan kulit. How he won the election............

Stop making a fuss on this matter. No action talk talk talk only lah nobita. Let us Sarawakians with full autonomy in education show you the real meaning to move forward

QUote: "qqq47660 > 6 minutes ago | Report Abuse

sted by qqq47660 > 1 second ago | Report Abuse

Yes, Caliph Yemen & Caliph Hamass deserve heaven and full respect. Others are cowards
==========


next hezbollah will declare war on Israel................expect escalation and no return to pre Oct 7."

Yes, Caliph Yemen, Caliph Hezbollah & Caliph Hamass deserve heaven and full respect. Others are cowards (including paspuspis & gang)

Quote: "qqq47660 > 15 hours ago | Report Abuse

d Hama is the representation of Muslim and Arab hearts and minds"

Yes, Caliph Yemen & Caliph Hamass deserve heaven and full respect. Others are cowards

HUAT ARRRRRRRRRRRR

Above are 3 key tips from someone who lives over 100 years and still feel like living in his tweenish era (it's me)

3. Declutter your heart cells (cardiomyocytes) by the EP program

The accumulation of glycated end products and amyloid in cells can have detrimental effects on various organs, including the heart. Autophagy, a cellular process responsible for degrading and recycling cellular components, can play a crucial role in reducing the risk of heart attack, aging-related cardiac issues, and heart failure by clearing these harmful substances.
Reduction of Oxidative Stress:
• Glycated end products and amyloid can lead to increased oxidative stress within cells. This oxidative stress can damage cellular components, including proteins, lipids, and DNA, and contribute to inflammation and aging of the heart.
• Autophagy helps to clear damaged cellular components, reducing oxidative stress and mitigating the detrimental effects on cardiac tissues.

Maintenance of Protein Quality:
• Autophagy plays a critical role in maintaining protein quality within cells. It identifies and selectively degrades misfolded, damaged, or aggregated proteins, such as amyloid.
• In the context of the heart, the clearance of amyloid can prevent the formation of toxic protein aggregates, which are often associated with cardiac diseases, such as amyloid cardiomyopathy.

Energy Homeostasis:
• Autophagy is involved in maintaining energy balance by recycling cellular components and providing nutrients when needed.
• Dysregulation of energy metabolism is linked to heart diseases, including heart failure. By efficiently recycling cellular components, autophagy can contribute to energy homeostasis in the heart.

Cardiomyocyte Health:
• Cardiomyocytes are the specialized muscle cells of the heart responsible for its contraction. Accumulation of glycated end products and amyloid within cardiomyocytes can impair their function.
• Autophagy helps clear damaged organelles and proteins from cardiomyocytes, preserving their health and function and reducing the risk of heart failure.

Prevention of Inflammation:
• Accumulated glycated end products and amyloid can trigger inflammation, which can damage heart tissues and promote the progression of atherosclerosis and plaque formation.
• Autophagy can limit inflammation by removing the triggers, thereby reducing the risk of heart attack and atherosclerosis.

Slowing Down Aging-Related Cardiac Changes:
• Aging is a major risk factor for heart diseases. Accumulation of damaged proteins and cellular components accelerates aging-related cardiac changes.
• Autophagy can slow down these aging-related changes by maintaining cellular homeostasis, reducing oxidative stress, and preserving the integrity of cardiac cells.

Reduction of Ischemia/Reperfusion Injury:
• Autophagy can also protect the heart during episodes of ischemia and reperfusion, which are associated with heart attacks. It helps clear damaged components and reduces the risk of cell death during these events.

2. Normalising hsCRP

High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation in the body. It is produced by the liver and released into the bloodstream in response to inflammation or infection. hsCRP levels are often measured to assess the degree of inflammation within the body, and they can be useful in various medical contexts, including the evaluation of risk factors for cardiovascular diseases like ischemic heart disease (IHD).
Inflammation and Ischemic Heart Disease (IHD): Ischemic heart disease, also known as coronary artery disease (CAD) or coronary heart disease (CHD), is a condition characterized by the narrowing of the coronary arteries that supply blood to the heart muscle. This narrowing is often due to the buildup of fatty deposits (atherosclerosis) in the arterial walls. IHD can lead to reduced blood flow to the heart, which may result in chest pain (angina) or, in severe cases, heart attacks (myocardial infarctions).
In recent years, research has indicated that inflammation plays a significant role in the development and progression of IHD. Chronic, low-level inflammation can contribute to the formation of atherosclerotic plaques in the coronary arteries. Inflammatory processes within the arterial walls can lead to the rupture of these plaques, triggering blood clot formation, and subsequently blocking blood flow, resulting in a heart attack.

hsCRP is a sensitive marker of systemic inflammation. Elevated hsCRP levels in the blood indicate ongoing inflammation in the body, even at low levels not typically detected by the standard CRP test. When hsCRP levels are high, it suggests that inflammation is present in the body.

The Evolutionary Origin of Autoimmune basis for Diseases, Mediated by Shared Last Universal Common Ancestor Antigens, Explains Molecular Mimicry and Autoantibodies Cross-Reactivity to Prevent Systemic Inflammation Leading to Damage to Insulin Receptors, Accelerated Atherosclerosis, and Ischemic Heart Disease.
Autoimmune diseases involve the immune system mistakenly attacking healthy cells and tissues in the body, leading to a range of disorders. While the causes of autoimmune diseases are complex and multifactorial, shared antigens from the Last Universal Common Ancestor (LUCA) may have contributed to these conditions, particularly in the context of insulin resistance due to damages to the insulin receptors, inflammation-mediated accelerated atherosclerosis, and ischemic heart disease.
The LUCA is the hypothetical common ancestor of all life on Earth and dates back billions of years. While LUCA and human evolution are separated by vast time scales, it's possible that common antigenic elements were conserved throughout evolution. This shared antigenic heritage may contribute to molecular mimicry and cross-reactivity in the immune system.

Molecular mimicry is a phenomenon where pathogens or foreign antigens share structural similarities with self-antigens, potentially leading to cross-reactivity. Over time, the human immune system has developed to recognize and respond to pathogens, some of which may have antigens resembling self-antigens. This mimicry can trigger the production of autoantibodies that mistakenly target self-antigens.

Systemic inflammation resulting from autoimmune responses can damage various tissues and organs, including insulin receptors, which play a crucial role in regulating blood glucose levels and preventing diabetes mellitus. By linking the origins of autoimmune diseases to shared LUCA antigens, this hypothesis suggests that understanding the evolutionary context of autoimmunity may provide insights into mechanisms to prevent systemic inflammation and subsequent damage to insulin receptors.

Low-grade systemic inflammation is also associated with accelerated atherosclerosis, a condition characterized by the buildup of plaque in arteries, and ischemic heart disease, which can result from reduced blood flow to the heart muscle. By better understanding the evolutionary basis of autoimmune diseases, we may uncover ways to mitigate the inflammation that contributes to atherosclerosis and ischemic heart disease.

Tips:

1. Reverse aging vessels

Understanding evolution to reverse aging by activating the SIR gene and optimizing individualized stress exposure and endurance is a comprehensive approach that has the potential to reduce the risk of cancer, heart disease, and promote longevity.

Evolutionary Insights: Evolutionary biology offers us insights into how our genes, including the SIR gene, have evolved over time to protect our species and ensure our survival. By understanding the genetic and cellular mechanisms that have evolved to maintain health and longevity, we can leverage this knowledge to address aging-related health issues.

Aging and Disease Risk: Aging is a significant factor in the development of many chronic diseases, including cancer and heart disease. As we age, our cells accumulate damage, and our body's repair mechanisms become less efficient. The SIR gene is associated with DNA repair and maintaining cellular health, making it a critical target for interventions.

Individualized Stress Exposure: Stress, when properly managed, can stimulate adaptive responses in the body. Individualized stress exposure acknowledges that the optimal level and type of stress may vary from person to person. By identifying an individual's stress threshold, we can design interventions that promote health and longevity while minimizing harm.

Cancer Risk Reduction: Individualized stress exposure and the activation of the SIR gene can potentially reduce cancer risk. Chronic stress and cellular damage are risk factors for cancer. By optimizing stress exposure and enhancing DNA repair, we can lower the likelihood of mutations that lead to cancer development.

Heart Disease Risk Reduction: Heart disease is closely linked to the aging process. By promoting cellular repair and health through SIR gene activation, we can mitigate the age-related factors that contribute to heart disease. Proper stress management and endurance training can also improve cardiovascular health.

Longevity and Healthy Aging: The ultimate goal is to extend human lifespan and promote healthy aging. By activating the SIR gene, reducing cellular damage, and optimizing stress exposure, we aim to slow down the aging process and maintain health and vitality into old age.

EngineeringProfit

15,869 posts

Posted by EngineeringProfit > 0 seconds ago | Report Abuse

2. The Evolutionary Origin of Autoimmune basis for Diseases, Mediated by Shared Last Universal Common Ancestor Antigens, Explains Molecular Mimicry and Autoantibodies Cross-Reactivity to Prevent Systemic Inflammation Leading to Damage to Insulin Receptors, Accelerated Atherosclerosis, and Ischemic Heart Disease.
Autoimmune diseases involve the immune system mistakenly attacking healthy cells and tissues in the body, leading to a range of disorders. While the causes of autoimmune diseases are complex and multifactorial, shared antigens from the Last Universal Common Ancestor (LUCA) may have contributed to these conditions, particularly in the context of insulin resistance due to damages to the insulin receptors, inflammation-mediated accelerated atherosclerosis, and ischemic heart disease.
The LUCA is the hypothetical common ancestor of all life on Earth and dates back billions of years. While LUCA and human evolution are separated by vast time scales, it's possible that common antigenic elements were conserved throughout evolution. This shared antigenic heritage may contribute to molecular mimicry and cross-reactivity in the immune system.

Molecular mimicry is a phenomenon where pathogens or foreign antigens share structural similarities with self-antigens, potentially leading to cross-reactivity. Over time, the human immune system has developed to recognize and respond to pathogens, some of which may have antigens resembling self-antigens. This mimicry can trigger the production of autoantibodies that mistakenly target self-antigens.

Systemic inflammation resulting from autoimmune responses can damage various tissues and organs, including insulin receptors, which play a crucial role in regulating blood glucose levels and preventing diabetes mellitus. By linking the origins of autoimmune diseases to shared LUCA antigens, this hypothesis suggests that understanding the evolutionary context of autoimmunity may provide insights into mechanisms to prevent systemic inflammation and subsequent damage to insulin receptors.

Low-grade systemic inflammation is also associated with accelerated atherosclerosis, a condition characterized by the buildup of plaque in arteries, and ischemic heart disease, which can result from reduced blood flow to the heart muscle. By better understanding the evolutionary basis of autoimmune diseases, we may uncover ways to mitigate the inflammation that contributes to atherosclerosis and ischemic heart disease.

Tips:

1. Reverse aging vessels

Understanding evolution to reverse aging by activating the SIR gene and optimizing individualized stress exposure and endurance is a comprehensive approach that has the potential to reduce the risk of cancer, heart disease, and promote longevity.

Evolutionary Insights: Evolutionary biology offers us insights into how our genes, including the SIR gene, have evolved over time to protect our species and ensure our survival. By understanding the genetic and cellular mechanisms that have evolved to maintain health and longevity, we can leverage this knowledge to address aging-related health issues.

Aging and Disease Risk: Aging is a significant factor in the development of many chronic diseases, including cancer and heart disease. As we age, our cells accumulate damage, and our body's repair mechanisms become less efficient. The SIR gene is associated with DNA repair and maintaining cellular health, making it a critical target for interventions.

Individualized Stress Exposure: Stress, when properly managed, can stimulate adaptive responses in the body. Individualized stress exposure acknowledges that the optimal level and type of stress may vary from person to person. By identifying an individual's stress threshold, we can design interventions that promote health and longevity while minimizing harm.

Cancer Risk Reduction: Individualized stress exposure and the activation of the SIR gene can potentially reduce cancer risk. Chronic stress and cellular damage are risk factors for cancer. By optimizing stress exposure and enhancing DNA repair, we can lower the likelihood of mutations that lead to cancer development.

Heart Disease Risk Reduction: Heart disease is closely linked to the aging process. By promoting cellular repair and health through SIR gene activation, we can mitigate the age-related factors that contribute to heart disease. Proper stress management and endurance training can also improve cardiovascular health.

Longevity and Healthy Aging: The ultimate goal is to extend human lifespan and promote healthy aging. By activating the SIR gene, reducing cellular damage, and optimizing stress exposure, we aim to slow down the aging process and maintain health and vitality into old age.

Belum belajar berdikari dan menyara hidup, sudah diajar demonstrasi dan memegang senjata bertempur

Great distraction! When the school children are busy to focus on foreign conflicts afar, they couldn't protest against inflation, depreciation of ringgit and misappropriation of public fund at the same time.

DickyMe > 4 weeks ago | Report Abuse

".. religion unites,"???

It divides people into factions, it creates chaos and bloodbath.
Millions of lives have been sacrificed in the name of religion over the millenniums.
Religion has a gory history.

Together with the West Bank, their land area is comparable to Singapore. So is the strength of natural resources

What could be more disheartening than a country's leader who places the welfare of their people on the backburner? In an unfortunate twist of fate, over RM100 million of hard-earned taxpayers' money is set to vanish in the blink of an eye. This disheartening revelation unfolds amidst a backdrop of overwhelming foreign debt, a seemingly ill-timed reduction in post-pandemic subsidies, a dwindling budget for crucial components of healthcare, including hospitals, doctors, medications, and overall public health. Just last week, we witnessed over RM1 million slipping away from the coffers of Selangor, and the alarming truth is that more may follow. It's a stark reminder that donations should unequivocally originate from the pockets of individual politicians themselves. Public funds, a precious resource, should be handled with the utmost care and directed prudently to serve the best interests of the citizens who entrust their well-being to their leaders.

NO DAP from the start- remember what the ex finance minister condemn us Sarawak

I didn't vote for this gomen. I voted GPS. And GPS has promised to combined with PN to form gomen. Period

QUote: "Stop the protest as a first step"

Agree. Those who choose to continue the human shield propaganda should just march all the way there using personal saving. Period.

Would you say Singapore should relocate to China?

Singapore's decision to establish a consulate office in Kuching marks a significant milestone in strengthening the bilateral relations between Sarawak and the Republic of Singapore. This move reflects a shared commitment to fostering greater cooperation and understanding between the two regions.

The establishment of a consulate in Kuching not only signifies a diplomatic achievement but also a bridge of connectivity and collaboration. It symbolizes the desire of both parties to facilitate smoother exchanges, promote trade, and enhance cultural ties.

Through this consulate, the people of Sarawak and Singapore can look forward to increased opportunities for engagement in various sectors, including trade, education, tourism, and cultural exchange. It paves the way for a deeper and more dynamic partnership that benefits both regions.

This development is a testament to the enduring spirit of diplomacy and collaboration, and it reaffirms the commitment to building stronger relationships that will endure for generations to come. It is a positive step towards a future marked by shared prosperity and mutual respect between Sarawak and Singapore.

Quote: " DickyMe > 2 hours ago | Report Abuse

Whatever argument you put forward, twist and turn, roll in roll out, quote all the books verses, it still does not justify killing of innocence. Remove your religious mask and think like a human being. It only require basic common sense, nothing complex. It is intentionally made complex for their selfish need."

Exactly. Why they want to show their hypocrisy and bigotry colour? It's a fact- in humanity we stand together; with faith we drift apart. Sanity is just so hard because of all the deluded preachers.

No matter how convoluted the arguments may become, no matter how they twist and turn, quoting verses and referencing texts, there is one fundamental truth that remains unaltered: the taking of innocent lives cannot be justified. It's a simple matter that transcends the boundaries of religion or ideology and appeals to our shared humanity.

We don't need elaborate theological discourse to recognize the intrinsic value of human life. Basic common sense tells us that the intentional taking of innocent lives is a grave injustice that defies any ethical or moral code. In the pursuit of their own selfish agendas, some may attempt to cloak such actions in complexity, but the core principle remains straightforward and universal.

This is a call to remove the veils of religious or ideological justification and to think as human beings. It's an appeal to the basic compassion and empathy that reside in every one of us. When innocent lives are at stake, there is no room for obfuscation or rationalization. The essence of this message is simple and clear: let us stand together in defense of life, in the name of our shared humanity.

speakup > 1 hour ago | Report Abuse

War is not a boxing match where spectators encourage their favourite boxer to whack the other.

i3lurker

13,021 posts

Posted by i3lurker > 1 hour ago | Report Abuse

My main concern now is whether go MacDee or Kepci for breakfast.


EngineeringProfit

15,851 posts

Posted by EngineeringProfit > 2 minutes ago | Report Abuse

Just remember to boykott coca-cola ya


EngineeringProfit

15,851 posts

Posted by EngineeringProfit > 48 seconds ago | Report Abuse

Quote: "War is not a boxing match where spectators encourage their favourite boxer to whack the other."

It is. Otherwise why some small insignificant busybody country with bad debt pushes so hard to deploy their troop with borrowed money. Why why tell me why

speakup > 1 hour ago | Report Abuse

War is not a boxing match where spectators encourage their favourite boxer to whack the other.

i3lurker

13,021 posts

Posted by i3lurker > 1 hour ago | Report Abuse

My main concern now is whether go MacDee or Kepci for breakfast.


EngineeringProfit

15,851 posts

Posted by EngineeringProfit > 2 minutes ago | Report Abuse

Just remember to boykott coca-cola ya


EngineeringProfit

15,851 posts

Posted by EngineeringProfit > 48 seconds ago | Report Abuse

Quote: "War is not a boxing match where spectators encourage their favourite boxer to whack the other."

It is. Otherwise why some small insignificant busybody country with bad debt pushes so hard to deploy their troop with borrowed money. Why why tell me why

speakup > 1 hour ago | Report Abuse

War is not a boxing match where spectators encourage their favourite boxer to whack the other.

i3lurker

13,021 posts

Posted by i3lurker > 1 hour ago | Report Abuse

My main concern now is whether go MacDee or Kepci for breakfast.


EngineeringProfit

15,851 posts

Posted by EngineeringProfit > 2 minutes ago | Report Abuse

Just remember to boykott coca-cola ya


EngineeringProfit

15,851 posts

Posted by EngineeringProfit > 48 seconds ago | Report Abuse

Quote: "War is not a boxing match where spectators encourage their favourite boxer to whack the other."

It is. Otherwise why some small insignificant busybody country with bad debt pushes so hard to deploy their troop with borrowed money. Why why tell me why

Quote: "War is not a boxing match where spectators encourage their favourite boxer to whack the other."

It is. Otherwise why some small insignificant busybody country with bad debt pushes so hard to deploy their troop with borrowed money. Why why tell me why

Just remember to boykott coca-cola ya

Play up their emotion to the max. When the leave to join ha-isis-mas, retract their citizenship. So we don't get bombarded to the ground

Boikot coca-cola ya

DAP = dumb, apathy & pernicious
= MCA 2.0

Toy= cheat. Should be honestly real. For real. And pack them to the frontline. Human shield against laser beam

Quote: "....the fittest seems to be one of the dumbest religion"

Everything evolves as such for a reason. Has to be this way. You know why