With the financial aid of a biotechnology executive whose daughter may need a lung transplant, U.S. researchers have been shattering records in xenotransplantation, or between-species organ transplants.
The researchers say they have kept a pig heart alive in a baboon for 945 days and also reported the longest ever hidney swap between these species, lasting 136 days. The experiments used organs from pigs “humanized” with the addition of as many as five human genes, a strategy designed to stop organ rejection.
The GM pigs are being produced in Blacksburg, Virginia, by Revivicor, a division of the biotechnology company United Therapeutics. That company’s founder and co-CEO, Martine Rothblatt, is a noted futurist who four years ago began spending millions to supply researchers with pig organs and has quickly become the largest commercial backer of xenotransplantation research.
Rothblatt says her goal is to create “an unlimited supply of transplantable organs” and to carry out the first successful pig-to-human lung transplant within a few years. One of her daughters has a usually fatal lung condition called pulmonary arterial hypertension. In addition to GM pigs, her company is carrying out research on tissue-engineered lungs and cryopreservation of organs. “We’re turning xenotransplantation from what looked like a kind of Apollo-level problem into just an engineering task,” she says.
Some researchers agree with Rothblatt that the latest results mean pig-to-human transplants are plausible. “I think it’s possible; it should be considered,” says Leo Bühler, a Swiss transplant surgeon in Geneva. He said he would transplant a genetically engineered pig’s organ into a patient today, were the patient’s situation desperate enough.
And there are desperate cases. In fact, thousands of people die each year while waiting on transplant lists. Donated human organs are scarce, and many that become available don’t end up helping anyone. That is because a heart or kidney lasts only a matter of hours packed in ice, so organs can’t reach any but the closest patients.
“We want to make organs come off the assembly line, a dozen per day,” says Rothblatt. In 2011 her company paid about $8 million to take over Revivicor, and she has outlined plans for a facility able to breed 1,000 pigs a year, complete with a surgical theater and a helipad so organs can be whisked where they are needed.
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I think they chose pigs because pigs are genetically gery similar to human. Almost 97%, if I am not wrong
2015-08-13 17:45
yes... actually for thousand and thousands (perhaps millions) of years human had tamed pigs for their consumption...
you can even see the jungle people in papua..
or the Amazon tribes..
surely got pigs being rared.
our body has evolved to eat pigs
so probably genetically also very compatible (not sure there is a link ;)! )
2015-08-13 17:49
Research indicates that humans evolved from primates. Is it then possible that isolated humans evolved into pigs?
2015-08-13 17:58
from less intelligent can become more intelligent
but not the other way around..
so from humans to pigs not possible
may be from primate to pigs can..
however there is one possibility
that humans can transform to ape/primate
that's when they reproduce too much
n have too much voting power
brainwashed by all these 'beliefs'..
or u can say with higher strength of belief as..'religion'
2015-08-13 18:04
U will be surprised what I found when I googled this topic
http://www.dailymail.co.uk/sciencetech/article-2515969/Humans-evolved-female-chimpanzee-mated-pig-Extraordinary-claim-American-geneticist.html
If anybody found the link offensive, please don't flame me. I didn't write it
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Posted by TECHfullyBREWED > Aug 13, 2015 05:58 PM | Report Abuse
Research indicates that humans evolved from primates. Is it then possible that isolated humans evolved into pigs?
2015-08-13 18:12
Techfullybrewed it is a pleasure to meet you. Are you an individual or institution ? If you don't mind I ask. I am just curious
2015-08-13 18:14
Ah, it is so refreshing to chit chat with somebody about something not related to money. I haven't felt so good for a long time. A lot of greed, fear, attacks and abuses exist in this forum. I sometime found it tiring.
2015-08-13 18:15
ha ha hah...very interesting article there Icon!
Just look at Kim Jong Un!
Surely his grandma mated with fat pig...
"These distinguishing characteristics, including hairless skin, a thick layer of subcutaneous fat, light-coloured eyes, protruding noses and heavy eyelashes, to name but a few, are unmistakeably porcine, he suggests.
There are also a number of less obvious but equally inexplicable similarities between humans and pigs in the structure of the skin and organs.
Indeed, pig skin tissues and heart valves can be used in medicine because of their similarity and compatibility with the human body."
2015-08-13 18:18
Are you a stockmarket investor ? You are quite new here. So far I haven't seen u participated in discussion of particular stocks
2015-08-13 18:26
Humans are known to 'instinctively' have unusual/unnatural sexual preferences, including beastiality.
2015-08-13 18:40
Err.... No comments on that... Ha ha ha
But my lecturer used to tell us that they once entered a jungle to do research. The researchers are men, and an old aunty came along to cook for them (no offense to old aunties, please). After few weeks in the jungle, they began to find the old aunty quite attractive, ha ha
2015-08-13 18:45
Yes i am an investor. I've been reading your excellent articles since PRIVASIA.
2015-08-13 18:46
in outback aussie land... some aussie screw the kangaroo... why do u think kangaroo jumping around?
Posted by Icon8888 > Aug 13, 2015 06:45 PM | Report Abuse
Err.... No comments on that... Ha ha ha
But my lecturer used to tell us that they once entered a jungle to do research. The researchers are men, and an old aunty came along to cook for them (no offense to old aunties, please). After few weeks in the jungle, they began to find the old aunty quite attractive, ha ha
2015-08-13 18:48
Techfullybrewed, I found you interesting because the articles you posted are quite unique. Unlike other people who cut and paste like a machine, your choice of articles usually provide unique insights into certain things. I can see the thoughts behind it
2015-08-13 18:49
Duit I definitely not talking about you lah. Your articles better than read comics
By the way, can you do me a favor ?
2015-08-13 18:57
can you write an article about Aussie, Kangaroo and crocodile ?
and if you have spare time, maybe also add in the story how the pig fell in love with the chimpanzee ?
http://www.dailymail.co.uk/sciencetech/article-2515969/Humans-evolved-female-chimpanzee-mated-pig-Extraordinary-claim-American-geneticist.html
2015-08-13 19:09
hey why they never make Zoo as a public listed company?
this way surely all the animals can be taken care of..
2015-08-13 19:14
i was told a family in some outback state like kelantan capture a female orang utan. and make her dress shirt and make up and there r always long q of ppls waiting to have sex with her and pay a fee.
anyone heard?
2015-08-13 19:16
Really? I m on short trip.. After business meeting and sign off with my corporate lawyer then fly back..
NT feeling well lately macam nak cari alasan to skip only
TF... Macam mustahil saje
2015-08-13 19:19
TF...
ICON SHOULD NOT ANSWER.. Judge will ques Defenden.... Plaintif must show proof also....
If Icon answer mean Icon rape the female orang hutan lo
2015-08-13 19:21
duit I go Auckland to see KC Chong. But don't know whether he wants to see me or not
Posted by duitKWSPkita > Aug 13, 2015 07:19 PM | Report Abuse
Really? I m on short trip.. After business meeting and sign off with my corporate lawyer then fly back..
NT feeling well lately macam nak cari alasan to skip only
TF... Macam mustahil saje
2015-08-13 19:23
Icon... U ad very GENG... No need to polish la... U should collect 徒弟now..
TF... Icon so bad... That time we had bakuteh party.. He raped all my steel robots at garden... Now almost due to deliver steel baby lo
2015-08-13 19:26
Probability
wah...pig is so useful to humans...in so many ways..
it should be worshipped...
I really wish this genetic modification cannot be applied for animals other than pig...
coz only those who are 'not so certain' wont be going to heaven (kafir la..)
deserve such transplants.
2015-08-13 17:38