GENTING BHD

KLSE (MYR): GENTING (3182)

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Last Price

4.52

Today's Change

-0.12 (2.59%)

Day's Change

4.50 - 4.64

Trading Volume

12,814,600


43 people like this.

83,558 comment(s). Last comment by AngTayKor 1 hour ago

Posted by birkincollector > 2022-10-07 09:35 | Report Abuse

perhaps more sins tax in today budget?

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 09:40 | Report Abuse

I guess to some ppl glove + casino cannot coexist lol

MoneyMakers

7,496 posts

Posted by MoneyMakers > 2022-10-07 09:43 | Report Abuse

“TauRx Alzheimer trial failed to deliver pre-specified analyses - plans to seek approval anyway”

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 09:46 | Report Abuse

They are trying to persuade to get approval from a different angle
I don't know if that is right way or not, thus I'm not giving it any credit for now
I wouldn't give credit for something which is pretty much unknown to me

But ATK did say it was "proven", so ask him instead

Serious

175 posts

Posted by Serious > 2022-10-07 09:54 | Report Abuse

@ MoneyMakers
Please share link regarding your comment.

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 10:09 | Report Abuse

There are 3 types of approval:

1. Pre-specified endpoints.

2. Biomarkers. For Aduhelm FDA was using reduction in amyloid deposits. For taurx case, rate of brain atrophy us being used. Rate of brain volume atrophy is the scientifically best measurement to prove drug efficacy because AD patients' brains will all shrink due to dying brain cells.

3. When pure placebo is unfeasible (as seen in taurx's case), use ADNI historical placebo patients' performance for all the previous clinical trials done. There is ready pool of data probably 10k of placebo patients for all the past decades of AD clinical trials

There is no way Taurx is able to do double-blinded trial patients due to harmless blue pee side effects for our clinical trials without causing Therapeutic Active Placebo (TAP).

Posted by birkincollector > 2022-10-07 10:17 | Report Abuse

so why so many conflicting reports?? some said good, some no......so the conclusion?

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 10:19 | Report Abuse

**************************************************************
ABLE TO REVERSE DISEASE PROGRESSION (MCI PATIENTS)
**************************************************************

In the 105 participants with MCI (baseline MMSE score 23) receiving the 16 mg/day dose, there was statistically significant cognitive improvement of 2 units over the pre-treatment baseline at 6 months (p=0.0002), 12 months (p=0.0391) and 18 months (p=0.0473) on the ADAS-cog13 scale. The mean change on the instrumental activities of daily living subscale of ADCS-ADL also remained above the pre-treatment baseline at 6, 12 and 18 months.

**************************************************************************
ABLE TO HALT DISEASE PROGRESSION (MILD & MODERATE PATIENTS)
***************************************************************************
In the 147 participants with mild to moderate AD (baseline MMSE 20) receiving 16 mg/day, there was a 2.5 unit cognitive decline in the first 9 months and no further decline over the following 9 months. The functional decline on the ADCS-ADL scale was -2 units at 12 months and -3 units at 18 months representing a reduction in decline of about 75% relative to a published meta-analysis of publicly available placebo decline data from historical trials in mild to moderate AD

magellan

39 posts

Posted by magellan > 2022-10-07 10:20 | Report Abuse

AngTayKor, your call was correct.
You nailed it.
Profits.
Tks.

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 10:21 | Report Abuse

Sibei soong.... today up big again....... $$$$$ (each $=rm100,000/= profits)

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 10:23 | Report Abuse

I believe I am a typical noob in medical
Based on my understanding, one of the indicator is not showing good result (due to it being tainted)
I think the critical question is whether any other drug was approved in the past even if that same indicator is not positive, or the indicator can still be clinically approved using a different indicator?

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 10:24 | Report Abuse

For professional cha cha dancers, safety always come first. Haha :)

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 10:25 | Report Abuse

If Aduhelm can be FDA approved even without completing both trials (Biogen stopped the trials halfway thru), what do you think?

MoneyMakers

7,496 posts

Posted by MoneyMakers > 2022-10-07 10:31 |

Post removed.Why?

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 10:34 | Report Abuse

Well, few more reasons not to cheer, was the selling by LKT and son, at the peak of the previous "good news"
As they say, fool me twice shame on me lol
The other possible reduced reaction, is probably the impact can only be felt in FY2024, and many things can happen in between

Serious

175 posts

Posted by Serious > 2022-10-07 10:56 | Report Abuse

I guess we have to accept the matter of the fact that nothing is confirmed until it is really confirmed.

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 10:58 | Report Abuse

Not sure when is that confirmation coming, maybe early 2023

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 11:03 | Report Abuse

MoneyMakers, to be fair, "cannot differentiate test vs placebo", is not in the performance sense
I just did a short crash course on "placebo effect" and "active placebo" via google
You need to understand the proper placebo purpose and the placebo effect to understand this matter

After understanding it now, I would like to know what was the result of the "placebo" irregardless of the efficacy of the placebo test

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 11:06 | Report Abuse

The theory behind is that patients under placebo (fake administration of the drug), should not be able to tell they are a placebo, but in this case, they are able to tell due to the color of urine.

Sometimes a placebo can have a self-induced improvement just because they believed they are taking the real drug

Posted by WinBigOrLoseAll > 2022-10-07 11:33 | Report Abuse

people are worrying being cut vege again by the boss, so this time they smart and run first

WinSSP

323 posts

Posted by WinSSP > 2022-10-07 11:52 | Report Abuse

Resorts World Langkawi is nice to visit!

WinSSP

323 posts

Posted by WinSSP > 2022-10-07 11:56 | Report Abuse

Ai yo yo, TR KS ATK posted made porfeet….when Red. Profits made only when Green, faham tak?

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 12:07 | Report Abuse

Posted by WinSSP > 3 minutes ago | Report Abuse
Haha, don’t listen to fake, unlicensed TR KS ATK…. This is only public chat forum.
---------------------------------------------------------------------------

Aiyo sour grapes losers no need to come here and control what people think la. Got skill no skill people know la. ATK make $$$$$ money. ATK trade stocks to win money. Your own money your own decision. Sour grapes Losers can post all the rubbish she wants but still not make any money. Hahaha....... Huat Huat Huat Ah..... $$$$$

MoneyMakers

7,496 posts

Posted by MoneyMakers > 2022-10-07 12:08 |

Post removed.Why?

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 12:24 | Report Abuse

Posted by WinSSP > 11 minutes ago | Report Abuse
Ai yo yo, TR KS ATK posted made porfeet….when Red. Profits made only when Green, faham tak?
---------------------------------------------------------

Aiyo got people really so dumb meh? Typical sour grapes la..... Smart traders bought low from 4.32 onwards. Now price still 4.49, how not to make profit? Real low average buy price mah, not those fake investor's 4.50, 4.20, 4.00, 3.50 type of auto dropping average buy price. So simple but still cannot understand? Anyway, safety first OK? Understand??? Huat Huat Huat Ah!!! $$$$$

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 12:29 | Report Abuse

Oh gosh, this is deep, yeah further reading the report, I see that they used MTC as a disguise
I guess I'll just stick back to valuing this as a zero for now

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 12:38 | Report Abuse

Fierce bear market trade long also can profit. Not so simple. Precision in timing is everything. Precision timing is the best friend to the professional cha cha dancers.

ATK going to take a well deserved break. Going for a swim and drink my orange juice by the poolside.

1invest1

1,467 posts

Posted by 1invest1 > 2022-10-07 13:27 | Report Abuse

AngTayKor may have bought low sold high
Sure made profits.
If bought low 4.32, sold low 4.48, profit
If he bought 4.36, sold low 4.48, profit
He can read stk & situation well

choysun

4,313 posts

Posted by choysun > 2022-10-07 13:28 | Report Abuse

The way I read it, effectiveness of drug was good. Just can't reference placebo since it's not possible to create the blinded test environment. Ok la, wait for approval :)

choysun

4,313 posts

Posted by choysun > 2022-10-07 13:29 | Report Abuse

Congratulations to cha cha profits

Posted by WinBigOrLoseAll > 2022-10-07 14:28 | Report Abuse

Nov2022 if approved then only will big up, worthy to gamble or not?
Genting is always a place for big or small, come and bet

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 14:47 | Report Abuse

Nov 2022 only a conference to discuss
Approval date isn't known

limkokthye

6,039 posts

Posted by limkokthye > 2022-10-07 15:18 | Report Abuse

Pump and dump

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 15:35 | Report Abuse

Posted by choysun > 1 hour ago | Report Abuse
Congratulations to cha cha profits
----------------------------------------------------

Choysun is a sharp observer also. A professional also. Check back the records.


---------------------------------------------


Posted by choysun > 1 week ago | Report Abuse
Reversal time :)
-------------------------------------------


Good price action observation @Choysun. Ever considered to become a career professional cha cha dancer? :p

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 15:51 | Report Abuse

Posted by choysun > 2 hours ago | Report Abuse
The way I read it, effectiveness of drug was good. Just can't reference placebo since it's not possible to create the blinded test environment. Ok la, wait for approval :)
--------------------------------------------------------

Yes the result was way below my expectations for pre-specified endpoints. But it was above my expectation that MCI patients on the average can improve cognition and functional scores. The is called disease reversal. For mild and moderate patients, able to halt the disease is within my expectation.

All the trial patients have AD (brain scanned for amyloid deposits even though Lucidity is a Tau based trial). No way AD patients can score better or stop cognition decline if the drug does not work. Under such an outcome due to TAP (Therapeutic Active Placebo) issues, any JV licensing deals with big pharmas will have to wait until Taurx finishes the extra open label 12 mth extension with all the full data. Everyone will want to be on the cautious side. As I mentioned this morning abt the 3 ways of securing regulatory approvals, I believe Taurx shd be able to secure Conditional Marketing Approval to start commercialising HMTM but the authorities will need Taurx to conduct another larger and longer duration confirmation trial.

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 16:01 | Report Abuse

Posted by 1invest1 > 1 hour ago | Report Abuse
AngTayKor may have bought low sold high
Sure made profits.
If bought low 4.32, sold low 4.48, profit
If he bought 4.36, sold low 4.48, profit
He can read stk & situation well
--------------------------------------------

It is true that ATK bought plenty at 4.32 to 4.34. None was bought at the precise low of 4.31 because my buy q at that level didnt get hit 2 weeks ago.

But ATK "safety first" this morning, plenty from opening 4.64 to 4.69. You saw those very few volume done today at 4.69? Those were sold by yours truly here. Precision charting, precision timing, dare to strike at the right moment.

AngTayKor

1,904 posts

Posted by AngTayKor > 2022-10-07 16:02 | Report Abuse

Losers always like to accuse ATK fake trader. ATK shy shy show a bit of my red underwear colour here. Sold right at the peak. Sibei soong ah....

Oct 7 2022 9:13 AM
Withdrawn Partially
20,200
Oct 7 2022 9:02 AM
Part Done
4.69
1,300
20,200
Oct 7 2022 9:01 AM
Part Done
4.69
2,500
21,500
Oct 7 2022 9:01 AM
Part Done
4.69
20,000
24,000
Oct 7 2022 9:01 AM
Part Done
4.69
1,200
44,000
Oct 7 2022 9:01 AM
Part Done
4.69
4,800
45,200
Oct 7 2022 8:57 AM
Received
50,000

1invest1

1,467 posts

Posted by 1invest1 > 2022-10-07 16:34 | Report Abuse

Choysun is pretty accurate at GB pricing

1invest1

1,467 posts

Posted by 1invest1 > 2022-10-07 16:45 | Report Abuse

AnyTayKor
Without a doubt, you'll a sharpshooter.
Winner at GB share trading.

RWG

1,051 posts

Posted by RWG > 2022-10-07 17:40 | Report Abuse

lim guan eng win next election, genting sure die, cukai judi naik 50%

Posted by Michael_chan2022 > 2022-10-07 18:05 | Report Abuse

https://www.reuters.com/world/china/china-party-congress-looms-signals-sought-easing-covid-policy-2022-10-06/

After goreng Taurx news.. next will be re-opening of China border

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 18:28 | Report Abuse

Opening of China border is the biggest card left

bang_miskin

1,059 posts

Posted by bang_miskin > 2022-10-07 18:41 | Report Abuse

Nobody knows when China will open up, but JP Morgan and Goldman Sachs predict relaxation policies by second half of 2023 (April or May at the earliest).

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 20:11 | Report Abuse

There's talk of opening to appease citizens cum election this 16th Oct. Too many speculations around.
In anyway, the opening could actually lift the whole market sentiment

bang_miskin

1,059 posts

Posted by bang_miskin > 2022-10-07 20:33 | Report Abuse

Unlikely. They would rather wait until after the "Two Sessions" some time around March 2023. Even if China decides to open next year, they would not open up at once. They may test out some cities to avoid a sudden spike in cases.

Again all these are speculations because it all depends on one very important person, and he ain't saying anything about opening up yet.

DestinyL

4,740 posts

Posted by DestinyL > 2022-10-07 21:30 | Report Abuse

Good points.
The twenty big meeting on 16th this month may pave the way too. Relaxations have already started as well, Macau is example.

newbie2019

1,729 posts

Posted by newbie2019 > 2022-10-07 21:42 | Report Abuse

pump and dump….

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